6-Methylpyridine-2(1H)-thione
نویسندگان
چکیده
There are two unique mol-ecules in the asymmetric unit of the title pyridine-thione derivative, C(6)H(7)NS, each of which adopts the thione rather than the mercaptan form. The rings in both mol-ecules are essentially planar, with maximum deviations from the least-squares planes through all non-H atoms of 0.021 (2) and 0.017 (2) Å. In the crystal structure, the mol-ecules form centrosymmetric cyclic dimers through inter-molecular N-H⋯S hydrogen bonds. Additional C-H(meth-yl)⋯S inter-actions generate a three-dimensional network.
منابع مشابه
Synthesis and biological evaluation of some 4-(1H-indol-3-yl)-6-phenyl-1,2,3,4-tetrahydropyrimidin-2-ones/thiones as potent anti-inflammatory agents.
Twelve new 4-(1H-indol-3-yl)-6-phenyl-1,2,3,4-tetrahydropyrimidin-2-ones/thiones (7-18) have been synthesized by reacting 1-aryl-3-(1H-indol-3-yl)-2-propen-1-one with urea and thiourea in ethanolic potassium hydroxide. Their structures have been confirmed by IR, 1H NMR and mass spectral data. The compounds were tested for their anti-inflammatory activity. Test results revealed that compounds sh...
متن کاملAminosilanes derived from 1H-benzimidazole-2(3H)-thione
Two new molecular structures, namely 1,3-bis(trimethylsilyl)-1H-benzimidazole-2(3H)-thione, C13H22N2SSi2, (2), and 1-trimethylsilyl-1H-benzimidazole-2(3H)-thione, C10H14N2SSi, (3), are reported. Both systems were derived from 1H-benzimidazole-2(3H)-thione. Noncovalent C-H···π interactions between the centroid of the benzmidazole system and the SiMe3 groups form helicoidal arrangements in (2). D...
متن کاملelectrokinetic chromatography, thin-layer chromatography, high-performance thin-layer chromatography, high-performance liquid chromatography (HPLC) with atmospheric pressure chemical ionization–mass spectrometry, reversed-phase HPLC with ultraviolet detection and gas chromatography with negative-ion chemical ionization–mass spectro-
Chem. Abstr. Serv. Reg. No.: 60-56-0 Deleted CAS Reg. Nos: 4708-61-6; 85916-84-3 Chem. Abstr. Name: 1,3-Dihydro-1-methyl-2H-imidazole-2-thione IUPAC Systematic Names: 1-Methylimidazole-2-thiol; 1-methyl-4-imidazoline-2thione Synonyms: 2-Mercapto-1-methyl-1H-imidazole; 2-mercapto-1-methylimidazole; mercazolylum; 1-methyl-1,3-dihydroimidazole-2-thione; N-methylimidazolethiol; 1-methyl-2-imidazole...
متن کامل[4,6-Dimethylpyrimidine-2(1H)-thione-κS]iodidobis(triphenylphosphane-κP)copper(I)
In the mononuclear title complex, [CuI(C(6)H(8)N(2)S)(C(18)H(15)P)(2)], the Cu(I) ion is in a slightly distorted tetra-hedral coordination geometry formed by two P atoms from two triphenyl-phosphane ligands, one S atom from a 4,6-dimethyl-pyrimidine-2(1H)-thione ligand and one iodide ion. There is an intra-molecular N-H⋯I hydrogen bond. In the crystal, π-π stacking inter-actions [centroid-centr...
متن کاملThe crystal structures of three 3-methyl-1H-1,2,4-triazole-5-thiones, including a second polymorph of 4-[(E)-(5-bromo-2-hydroxybenzylidene)amino]-3-methyl-1H-1,2,4-triazole-5(4H)-thione and a redetermination of 4-amino-3-methyl-1H-1,2,4-triazole-5(4H)-thione
The structures of three 3-methyl-1H-1,2,4-triazole-5-thione derivatives are reported. The structure of 4-amino-3-methyl-1H-1,2,4-triazole-5(4H)-thione, C3H6N4S, (I), has been redetermined with an improved model for the H atoms: the non-H atoms of (I) all lie on mirror planes in space group Pbcm, and the H atoms of the methyl group are disordered over two sets of reflection-related atomic sites ...
متن کامل